Women who have leukocytes (+++) on urine test are in relatively serious condition, usually if accompanied by red blood cells and pus cells, or there are other times such as epithelial cells at the same time, it can be diagnosed as acute pyelonephritis, due to bacterial infection caused by the aggravation of leukocytes, and if the presence of leukocytes (+++) is a relatively very serious situation, it can be through the urethral blood type of the upward mobility of the urinary tract Direct invasion or lymphatic pathway, can cause white blood cells appear (+ + +) serious situation. In addition, in the body’s immune system, urinary tract obstruction, vesicoureteral reflux or in the medical infection, urinary tract infection or other such as gynecological infections, can also be retrograde infection to the urethra, causing urine test when the appearance of leukocytes (+ + +) situation. In the clinical situation, patients will have frequent urination, urinary urgency, painful urination, and even the situation of hematuria in the naked eye. If the infection continues it can lead to acute glomerulonephritis or acute renal failure, requiring immediate hospitalization.