The main ingredient of Fitalin is diclofenac sodium, and ibuprofen are non-steroidal anti-inflammatory drugs, both can be used to treat knee pain; because each patient’s condition is different, the sensitivity to the drug is also different, so it is not certain that which drug is more effective. 1. Diclofenac sodium: clinically can be used to treat knee osteoarthritis, rheumatoid arthritis, rheumatoid arthritis, gouty arthritis and other causes of knee pain, for trauma and other factors leading to soft tissue pain in the knee also has a better therapeutic effect. 2. Ibuprofen: also belongs to a kind of non-steroidal anti-inflammatory drugs, clinically for all kinds of knee joint arthritis, nerve pain, soft tissue pain have a better analgesic effect. Both contraindications and adverse reactions are similar, prohibited for other non-steroidal anti-inflammatory drug allergy, pregnant and lactating women, asthma patients allergic to aspirin. Common adverse reactions are nausea, vomiting, dyspepsia, gastrointestinal bleeding and other gastrointestinal causes, skin rash, itching and other allergic reactions. It should be noted that the pain treatment should not exceed 5 days, can not drink alcohol during the consumption, over 60 years of age, bronchial asthma, liver and kidney insufficiency, coagulation mechanism or platelet dysfunction should be used with caution. It is recommended that patients go to the hospital, improve the auxiliary examination, according to the patient’s specific condition, under the guidance of a professional physician medication.