Noon fever after liver cancer intervention may be caused by ischemic necrosis of tumor and infection and inflammation. 1. Ischemic necrosis of tumor: after liver cancer interventional therapy, ischemic necrosis of local tumor is caused by embolization of hepatic artery and fever is caused by release of pyrogen from tumor cells, which suggests that the tumor is being necrotic and absorbed; in addition, if the tumor grows rapidly, ischemic necrosis of tissues may also cause cancer fever. 2. Infection and inflammation: after tumor interventional therapy, cancer cells affect the body’s ability to regulate body temperature, which makes the immunity lower and leads to inflammation, such as upper respiratory tract infection may cause fever at noon. It may also be bacterial infection, such as biliary tract infection, liver abscess, lung infection, peritonitis and so on causing midday fever. When midday fever occurs after liver cancer intervention, it is necessary to go to the hospital in time to clarify the cause of the disease and actively treat it under the guidance of doctors.