Myeloma generally refers to multiple myeloma, and the success rate of its stem cell transplantation needs to be decided according to the type of transplantation. The success rate of allogeneic hematopoietic stem cell transplantation can generally reach 60%~70%, and the success rate of autologous hematopoietic stem cell can be more than 90%, but the specific situation also needs to be related to the age of the patient, the disease state, the physical condition of the donor, and the situation of the leukocyte antigen mating type, and many other factors. 1. Age: The success rate of stem cell transplantation will be higher if the patient is younger and in better physical condition. However, if the patient is older and has other diseases, the success rate of stem cell transplantation will be lower. 2. Disease status: If the patient’s symptoms are mild, the success rate of stem cell transplantation will be higher, but if the symptoms are more serious, the success rate of stem cell transplantation will be lower. 3. the physical condition of the donor: if the quality of hematopoietic stem cells is good, the success rate of transplantation will be higher, on the contrary, it will be lower. 4. Leukocyte Antigen Matching: If the patient and the donor have a high degree of leukocyte antigen matching, the success rate of transplantation will be increased, on the contrary, the success rate of transplantation will be reduced. The specific situation needs to be evaluated by a professional doctor to make a decision, so that effective treatment can be carried out under the guidance of the doctor.