Patients with schizophrenia are preferred to take atypical antipsychotic drugs, such as risperidone, olanzapine and other drugs are better. 1. Risperidone: belongs to atypical antipsychotics, used in the treatment of chronic and acute schizophrenia, has a better effect on negative and positive symptoms and their accompanying emotional symptoms. It should be used with caution in patients with Parkinson’s syndrome and epilepsy, and should not be used by women during pregnancy, and the dose should be reduced in the elderly and patients with hepatic, cardiac and renal diseases. Adverse reactions are postural hypotension, extrapyramidal syndrome, constipation, rhinitis, rash, etc.. 2. Olanzapine: it belongs to atypical antipsychotics, mainly used in the treatment of schizophrenia, schizoaffective disorder, bipolar disorder manic episodes, etc. It is a multi-receptor action drug, which has better effect on positive and negative symptoms, and the main adverse reactions include drowsiness, weight gain, and abnormalities of blood lipids and glucose, etc. If the diagnosis of schizophrenia is confirmed, the dose should be reduced. If diagnosed with schizophrenia, it is recommended to go to a professional hospital for standardized treatment as early as possible to reduce the adverse effects of the disease.