Fasting blood glucose 16mmol/l, if accompanied by diabetic symptoms can be diagnosed as diabetes mellitus, there is a possibility of reversal, for diabetic patients to take intensive lifestyle intervention, drug therapy, metabolic surgery, pancreas or islet transplantation may be able to achieve the reversal of the reversal of the reversal of the need for blood glucose monitoring, but not all diabetes mellitus can be reversed. A fasting blood glucose level greater than 7.0 mmol/l with diabetic symptoms is diagnostic of diabetes. Reversal is possible and strategies include intensive lifestyle interventions, intensive glucose lowering, metabolic surgery and pancreas or islet transplantation. However, the chances of achieving a reversal of diabetes depend on a number of factors such as age, duration of disease, blood glucose, complications, etc., and not all patients can achieve a reversal. Patients with diabetes that cannot be reversed should adhere to long-term glycemic control, which is generally aimed at a fasting blood glucose of 4.4 mmol/L to 7.0 mmol/L, with a non-fasting blood glucose of not more than 10.0 mmol/L. Fasting blood glucose 16.0mmol/l, need to seek timely medical treatment to avoid the occurrence of diabetic ketoacidosis, lactic acidosis and other acute complications. For patients with reversal, regular review under the guidance of the doctor is also required.