When a patient with HFMD has diarrhea, the severity of the diarrhea should be used to determine how to deal with it. If the degree of diarrhea is not too heavy, the number of times is relatively small, the stools are not too dilute, and there is no obvious pain, it is only necessary to do some symptomatic treatment, you can apply montelukast to stop diarrhea, you can also take other oral medications to regulate intestinal flora. If the symptoms of diarrhea are heavy, dilute and watery, and the number of diarrhea is particularly high, because HFMD is likely to be accompanied by a decrease in water intake, rehydration therapy is needed to prevent dehydration. Rehydration is done by applying some medications intravenously to keep the patient from becoming dehydrated by giving him/her water and the associated energy. The treatment of HFMD is mainly symptomatic, and after the disease is cured, it is important to see if there is significant relief of diarrhea, and if there is no significant relief, other tests should be done to find the cause.