The manifestations of women during menopause include menstrual disorders, neurological changes, emotional changes, osteoporosis and so on. 1. Menstrual disorders: the decrease of estrogen level and low ovarian function during menopause manifest as menstrual disorders. 2. Neurological changes: mainly manifested as paroxysmal hot flashes and sweating, which are more serious in early menopause. 3. Emotional changes: mental symptoms mainly manifested as irritability, insomnia, irritability and so on. 4. Osteoporosis: mainly manifested as pain in bone and joint muscles, decrease in bone density, and increase in the probability of bone fracture. Perimenopause is a physiological excessive period, and those who have obvious symptoms should be regulated with medicines under the guidance of doctors in order to pass through the menopause safely.