If a patient has symptoms of breath-holding in the middle of the night, the following points should be considered: First, consider cardiogenic diseases, for coronary heart disease unstable angina, severe arrhythmias, acute myocarditis or when there is heart failure, there will be pulmonary stasis or coronary artery ischemia, stenosis, spasm, the above conditions will cause ischemia and lack of oxygen in cardiac muscle cells, there will be dyspnea, breath-holding, wheezing in the middle of the night The clinical symptoms of suffocation. Second, for respiratory system diseases in chronic bronchitis, chronic bronchial dilatation, chronic obstructive pulmonary disease, pulmonary hypertension, asthma, will lead to dyspnea, breathlessness, wheezing, decreased oxygen saturation and low partial pressure of oxygen in the middle of the night. Third, for patients with severe phytodysfunction, once cardiac neurosis occurs, there will also be patients with clinical manifestations of chest tightness, shortness of breath, and conscious breath-holding in the middle of the night.