Ephedrine nasal drops is a very widely used nasal drops in otolaryngology. It is mainly a vascular mucosal constrictor, which can eliminate the congestion and swelling of nasal mucosa in a very short period of time, relieve nasal congestion while constricting the blood vessels of nasal mucosa and reduce nasal bleeding. It is mainly used for acute rhinitis, acute sinusitis, allergic rhinitis during acute attacks, and also when rhinorrhea is bleeding. Clinically, it is a vascular mucosal constrictor, still has great side effects, it can quickly relieve nasal congestion, but after using the drug, the patient can appear rebound vasodilatation, making the symptoms of nasal congestion reappear, or even aggravate, resulting in patients repeatedly dropping the drug, after a long time can inhibit the movement of nasal mucosa cilia, long-term frequent use of the drug will damage the nasal mucosa, and can produce drug resistance and drug Long-term frequent use of the drug can damage the nasal mucosa, and can produce drug resistance and drug dependence, resulting in drug rhinitis and other serious consequences, and long-term application of ephedrine nasal drops have toxic side effects on the patient’s heart or increase the patient’s blood pressure induced arrhythmia, so the clinical application of ephedrine is recommended not to exceed 4 days.