The cause of penile cavernous sclerosis has not yet been studied, and there exists mainly the doctrine of leukomalacia injury, which may be associated with other diseases and bad habits. The cause of penile cavernous stiffness is unknown. The leukomalacia injury theory is the most widely accepted cause hypothesis, which suggests that a prolonged inflammatory response leads to repetitive microvascular injury or trauma, which allows the leukomalacia to remodel into fibrotic plaques that form the sclerosis. In addition, diabetes mellitus, hypertension, dyslipidemia, ischemic heart disease, erectile dysfunction, smoking, and excessive alcohol consumption are all risk factors for the development of sclerosing cavernous sclerosis. Although the cause is unknown, most penile cavernous sclerosis is reversible, if there is no obvious impact on life, generally do not need special treatment, such as lead to obvious penile curvature, erection pain, and obviously affect the life of the time to consider surgical treatment, such as the white membrane lengthening surgery. If abnormalities are found, please follow the advice of a professional urologist for systematic treatment.