Fever may be present during the active phase of ulcerative colitis, which can cause symptoms of sleeping and sweating, or it may be caused by environmental factors, psychosomatic factors, or a combination of other diseases. Ulcerative colitis is a chronic inflammatory bowel disease of unknown etiology, with typical symptoms of abdominal pain, diarrhea, and mucopurulent bloody stools. The disease is characterized by alternating episodes and remissions, and when it is in the active phase, symptoms of fever can occur, leading to the manifestation of sweating while sleeping. Sweating while sleeping can also occur in patients with ulcerative colitis when they are anxious or depressed. Sweating while sleeping can also be caused by other factors, such as high ambient temperatures and excessive clothing. When combined with other diseases, such as hyperthyroidism, diabetes, etc., due to metabolic abnormalities can also appear in the symptoms of sweating while sleeping. Patients with ulcerative colitis who experience symptoms of sweating while sleeping are advised to seek prompt medical attention to have the specific cause clarified by a medical professional and treated as soon as possible.