Current repair materials include titanium mesh and PEEK, and the advantages and disadvantages of these two materials are explained in detail. Among the materials used to repair the skull, titanium mesh is widely used in clinical practice, but there are many problems. The following is an introduction to the defects of titanium mesh. Defects of titanium mesh: 1, titanium mesh is a metal material with high thermal conductivity and poor thermal insulation, which can easily cause sensitivity to hot and cold reactions. 2, titanium mesh is taken to cover the repair, this way may cause cutting injury or wear to the scalp. 3, titanium mesh interferes with the transmission of radiation, and the results of CT and MRI examinations may be affected after surgery. 4. The titanium mesh material is not very hard and is easily collapsed and deformed by external forces. 5.Titanium mesh also has infection and rejection phenomenon after surgery. 6, titanium mesh shaping effect is not ideal, the material has greater flexibility, which may lead to asymmetric head shape, postoperative temporal muscle atrophy, etc. Polyetheretherketone peek material is an advanced material used clinically in recent years, after long-term clinical practice and research, confirmed that the performance is very good. peek advantages: 1, better tissue compatibility, stronger pressure resistance, more perfect shaping. 2. Through 3D reconstruction and 3D printing, the skull structure is highly restored and both sides are symmetrical after repair. 3.The properties of polyetheretherketone are also very close to human autologous cranial bone, with low rate of rejection and infection, which does not affect CT MRI and other examinations. 4.Embedded repair, smooth articulation, high comfort and high mechanical strength of material. 5.Strong impact resistance and good protection performance.