Tingling in the ears when flying is most commonly caused by inflammation, congestion, and edema of the tympanic membrane due to air pressure injuries. This is mostly due to mechanical and physical obstruction of the Eustachian tube, the only outlet of the middle ear cavity, which leads to abnormal function of the Eustachian tube. When the airplane rises and descends, it will cause the air pressure inside the eardrum to weaken relative to the air pressure outside the eardrum, and the air pressure will instantly appear to press the pressure to the eardrum, resulting in the eardrum’s congestion and edema, and this kind of pain will lead to otitis media in serious clinical cases, and in more serious cases, it will also lead to perforation of the eardrum.