Pap grade 1 clinically indicates that there is no lesion in the cervical epithelium, but it is still necessary to do HPV laboratory test because Pap grade 1 only indicates the result, but does not identify the existence of any cause of cervical cancer. High-risk HPV infection, if persistent, can lead to cervical epithelial lesions and even develop into cervical cancer. Therefore, when the result is normal, it is necessary to find out whether the cancer-causing cause exists or not, and it is still recommended to do HPV laboratory test. If there is high-risk HPV infection, it must be taken seriously. It is recommended that colposcopy should be done preferably, and then biopsy should be taken, so that the clinic can understand whether the cervical epithelium has been lesioned according to the pathological results, so that there will not be any missed diagnosis.