Vulvar sclerosing moss is a disease that is characterized by atrophy and thinning of the skin of the perineum and vulva. The lesions mainly involve the clitoris and its prepuce, labia minora, posterior labial union, and the perianal area. The clinical manifestations of the disease include lightening of the vulvar skin, itching of the vulva, and pain and burning sensation during sexual intercourse. Treatment is based on the use of sedative, anti-allergic and hormonal medications, as well as sleep. Patients need to keep the vulva clean and dry, avoid using irritating drugs or alkaline soap to wash the vulva, wear fat, loose cotton underwear, do not wear chemical fiber underwear, and forbid spicy, stimulating food. If the itching symptoms are heavy and cause insomnia at night, you can add some sleeping and sedative drugs as well as anti-allergy drugs as appropriate. Some patients with severe vulvar itching, especially at night, can be treated with local glucocorticoids, such as hydrocortisone, but should not be used for a long time. If the condition is very serious and the medication and general treatment are not effective, surgical treatment of vulva can be performed, such as vulvectomy and laser excision.