Liver function abnormalities caused by taking febuxostat can be given liver-protecting medications, such as liver protection tablets, glutathione, and diammonium glycyrrhizinate. Specifically should be used under the guidance of a doctor. The common adverse reactions of febuxostat are liver function impairment, others are thrombocytopenia, nausea, stomach pain and so on. It is contraindicated for patients who are taking azathioprine, mercaptopurine or aminophylline. If the condition really need to take the drug, can be instructed by the doctor to add liver protection drugs, can be selected according to the specific liver function. Commonly, there are liver protection tablets, biphenyl dibenzoate, glutathione, diammonium glycyrrhizinate and so on. If the condition permits, the medication can be stopped or replaced with other medications under the guidance of the doctor. Commonly available are Probenecid, Benzbromarone, Allopurinol, etc. Taking febuxostat caused liver function impairment, patients are advised to consult a doctor for specific treatment measures. All drugs should be used under the guidance of a doctor.