The soft and sore knees in the middle of the night may be caused by physiological reasons such as excessive activities during the day and lower temperatures at night, or it may be caused by pathological factors such as degenerative diseases of the knee joint and autoimmune diseases.
1. Physiological reasons: If the knee joint is more active during the day, such as people who often climb mountains and run, it may cause fatigue of the soft tissues around the knee joint, leading to the accumulation of metabolic products, increased vascular permeability, causing joint edema and symptoms of knee weakness in the middle of the night; in addition, if the temperature is low at night, and the knee joints are not warmed up in time, the above symptoms may also occur.
2. Pathological reasons: the degeneration of knee joint may cause osteomalacia, synovial hyperplasia and other changes in the knee joint, and at night due to parasympathetic innervation, there may also be symptoms of knee pain; in addition to the combination of autoimmune diseases, if there is involvement of the knee joint, there may also be the symptoms mentioned above, such as rheumatoid knee osteoarthritis, gouty knee osteoarthritis, and so on.
The symptoms of knee pain in the middle of the night alone sometimes can not accurately determine the cause, but also need to be combined with the characteristics of the medical history, other test results to make an accurate judgment, it is recommended to clarify the cause of the disease under the guidance of a doctor.