The principles of hemangioma treatment are: control growth, promote regression, and protect function and appearance. Some parents ask about the “best time for treatment”, but in fact, the growth of hemangioma varies greatly among individuals, and the growth site and growth rate of each infant and child are different. Therefore, we advocate “individualized treatment strategy”. Although hemangioma has the characteristic of self-resolution, it is uncertain when it will start to recede, to what extent it will recede, and what kind of deformity it may leave behind, and active intervention can speed up the process of receding, reduce the degree of deformity left behind, and relieve the anxiety of parents and children as soon as possible. Standardized and individualized treatment in regular medical institutions is generally effective, safe, and risk-controlled. Treatment of true hemangioma may vary from region to region, from medical unit to medical unit, and from physician to physician. Currently, the most common and proven treatments for hemangioma are as follows: 1. Propranolol, also known as insulin, which is an old drug for heart disease, soon became popular around the world after French doctors discovered by chance in 2008 that it has the effect of treating hemangioma. It is listed as the first-line drug in the 2016 and 2019 editions of our guidelines for the treatment of hemangioma vascular malformations. Heartland has positive results in treating true hemangioma and is inexpensive, making it very popular with some specialist physicians and with parents of children with hemangioma. However, it requires daily dosing and can take as long as six months to a year, or longer in some children. It is a torture for many parents to give the drug to their infants and children every day, and there may be rebound after stopping the drug. Moreover, Takuan may cause hypoglycemia, hypotension, slowed heart rate, asthma, and sleep disorders, and prolonged dosing may cause changes in liver and kidney function, cardiac enzyme profile, and thyroid function. It is a fat-soluble drug that can cross the blood-brain barrier, so it is a concern for scholars whether it will affect the cognitive ability of the brain and the development of the immature nervous system. Some scholars have observed that takayasu can affect both distant and near-term memory in humans. It is recommended that the treatment of takayasu should be carried out under the guidance of an experienced doctor. 2, oral glucocorticosteroids such as prednisone tablets, this is a common treatment method in the past, due to the serious side effects that may be brought about by long-term use of hormones, such as full moon face, buffalo back, Cushing’s syndrome, reduced immunity, etc. Now, unless propranolol and other methods are not suitable, and the need for systemic medication cases, so oral glucocorticosteroids. It is rarely used at present. 3.Laser treatment laser is effective for superficial type, point or small piece of hemangioma. Since the skin of infants and children is thin, laser treatment for hemangioma has high requirements on the penetration depth of the laser, which may not be effective if it is shallow and may leave scarring if it is too deep. The local cooling system during laser treatment has been improved, but there is no complete method for local pain relief in some areas. There is a certain recurrence rate after laser treatment of hemangioma, presumably because the laser destroys the proliferating hemangioma cells, but does not reduce or weaken the triggering factors for hemangioma growth. 4. Topical drugs such as propranolol ointment, thiaminolol cream, carteolol eye solution and thiaminolol eye solution are effective for superficial type of true hemangioma, which are simple, easy and inexpensive. If their permeability to hemangioma tissues can also be improved, their therapeutic effect and suitable range will be substantially increased, which is also a promising work being carried out by researchers. Topical drugs are suitable for early, very superficial hemangiomas. 5.Hemangioma local percutaneous perfusion treatment infuses drugs, mainly hormones and anti-tumor antibiotics such as bleomycin and pinyamycin, into the hemangioma tissue in a certain concentration or drug ratio, which can effectively inhibit the growth of hemangioma and promote its regression. Many parents have concerns about the use of hormones and anti-tumor antibiotics. After more than 30 years and more than 100,000 clinical treatments and long-term follow-ups, our clinical and research team found that percutaneous perfusion treatment of hemangioma is minimally invasive and reliable, and the amount of hormones and anti-tumor antibiotics used locally for hemangioma is very small and has no significant impact on the growth and development of children. There was no weakening. However, for a very small number of large hemangiomas that require large doses and high frequency treatment, the growth and development and resistance of the children are affected during the drug administration phase, but after stopping the drug, the children can gradually return to the level of their age. The infusion treatment of hemangioma tumor is effective, minimally invasive, with little side effects, safe, reliable, economical, simple and easy to use, but requires physicians to have more experience and skills. 6.Surgical treatment requires general anesthesia for infants and children, and it is traumatic and may cause damage to neighboring tissues and leave scarring, so it is an option for the above methods to be ineffective or for some special cases, and is relatively rare in clinical treatment. 7.There are some rare methods such as cryotherapy, which has been less used due to its pain and scar formation. Nucleoplasty, which has been abandoned due to the danger of radiation. High-frequency electro-acupuncture, which is limited in effectiveness and invasive, is still used in some units. Some hemangiomas can be closely observed and wait for their regression. Active intervention is desirable to speed up the process of hemangioma regression, reduce the appearance of posterior deformities, reduce the psychological impact of hemangioma on the child, control its growth, promote its regression, and protect function and appearance. In addition to the different growth sites, types, stages of growth or regression, the ratio of vascular endothelial cells to blood vessels in the body, and the experience and level of physicians in different regions, “individualized treatment” and different treatment plans are chosen to maximize the therapeutic effect. For parents of children with hemangioma, choosing a regular medical institution and an experienced specialist is the easiest and most important part of all treatment strategies.