Hemangioma is the most common benign tumor in infants and children, generally speaking, the incidence rate of newborns is about 2% to 3%, and up to 12% after 1 year of age. Preterm and low-birth-weight infants have a higher incidence of 20%, and the incidence in female infants is three times higher than that in male infants. About 80% of hemangiomas are solitary, i.e., one site, and 20% are multiple, i.e., multiple sites throughout the body. Some of the lesions may be associated with infection, hemorrhage, or ulceration, and a small number of hemangiomas may invade mucous membranes, muscles, bones, and intracranial areas, resulting in some physiologic dysfunction. Most hemangiomas exist at birth, and most of the rest appear within 1 month after birth. At the initial stage, they are often light red spots on the surface of the body without protruding from the skin, and then rapidly grow and merge into bright red plaques or lumps in a short time, indicating strawberry shape; however, the color of deep hemangiomas does not change obviously or is blue. Skin hemangiomas are divided into: simple capillary hemangioma (mostly appearing 3 to 5 weeks after birth. They are often found on the face, neck and trunk of the body. They are usually single or multiple, high above the skin surface, in the form of strawberry-like lobular pattern, with clear boundaries, soft texture, bright red, i.e. strawberry angiomas, and do not fade away when pressed), bright red nevus (also known as nevus of wine or nevus of dilated capillaries, which occurs mostly at birth or soon after birth), bright red nevus (also known as nevus of wine or nevus of dilated capillaries, which occurs mostly at birth or soon after birth). It occurs at birth or shortly after birth. It occurs on the head, neck and face, and is mostly unilateral. Those occurring on the forehead, bridge of the nose or occipital area can often subside on their own, while larger or widespread ones often persist for life. They are bright red patches that do not rise above the skin surface and fade with pressure. Spongiform hemangiomas (mainly venous formations, most often found at birth or shortly after birth. Most are found on the trunk and are often pigeon to egg sized. They are named after the spongy sensation when pressed locally. The tumor is elevated above the skin surface, nodular or lobulated, with unclear borders, soft and elastic, light purple or purple-blue in color, and can be significantly shrunken after squeezing. The surface skin is normal or adheres to the tumor and atrophies, located under the skin or mucous membrane, and may also occur in muscle, bone or viscera). Mixed hemangioma type 4, mixed hemangioma is a mixture of 2 or more types mentioned above, which can occur in various parts of the body, most often in the superficial part of the head and neck and limbs. The pathologic process is divided into 2 completely different stages, i.e. proliferative stage and regressive stage. Hemangiomas have a tendency to regress naturally at the age of 5 years, and a small number of children can completely regress at the age of 7-8 years. However, we should not wait blindly and negatively, and some strawberry hemangiomas can develop into mixed hemangiomas or cavernous hemangiomas. Some strawberry hemangiomas may develop into mixed hemangiomas or cavernous hemangiomas. 10% to 20% of the children with varying degrees of skin damage at the site of the lesion, most of which is the expansion of tiny blood vessels in the skin, whitening and wrinkling of the skin, or skin scars or atrophy, and large areas of hemangiomas may have localized skin laxity after the regression. Although, some infantile hemangiomas begin to subside on their own after the age of 1 year, proliferative hemangiomas may have various complications, such as ulcers, bleeding, infections, etc. which often lead to disfigurement. Negative waiting, no treatment and letting the natural development, the final outcome is different, the growth phase hemangioma due to tumor enlargement, thickening, even if the lesion subsides later, it will still leave cosmetic defects: scars, skin folds, pigment residue and so on. Especially hemangiomas located in the face and neck will cause greater psychosocial trauma to the children and their parents, so they should be detected at an early stage and treated in time. If the growth and proliferation of the lesion can be controlled at the early stage of proliferation, the damage to the skin appearance can be minimized and the skin appearance can be basically maintained. For example, hemangiomas located in special areas affect the aesthetics and their functions, especially hemangiomas of the eyelids and conjunctiva will affect vision; those located in the respiratory tract such as mouth, pharynx and nose will lead to respiratory disorders. Especially for cavernous and mixed hemangiomas, the possibility of natural regression is extremely low, and it is necessary to carry out active treatment in time to control its development and cure it as soon as possible. Common treatments include isotope application, laser therapy, liquid nitrogen freezing, local injection of sclerosing agent or paxillin, oral hormone, tumor restraint, interventional therapy and surgical resection. Since 2008, when propranolol (propranolol) was firstly introduced in New England Medicine for the treatment of hemangiomas, there have been reports of successful treatment of hemangiomas with cardiac glycosides at home and abroad, which are mainly used for large tumors and special areas that are not suitable for dressing treatment, and are usually taken at once with 1mg/kg. The treatment process requires special attention to the side effects of Cardioplegia in children: slowing down of heart rate, lowering of blood pressure, hypoglycemia, bronchospasm and so on. The physician will choose a different method of treatment depending on the age of the child, the location of the tumor, its type, morphology and progression. Comparatively speaking, the isotope dressing method is simple and easy to implement, without leaving scars, especially for the facial area of the treatment effect is good. Isotope dressing treatment of cutaneous hemangioma has been carried out in China since 1958 and has accumulated many years of clinical experience. Experience has proved that isotope dressing treatment of hemangioma by using β-ray is a mature treatment method with good effect, simple and convenient, and it is economical, safe and painless and harmless to children. Radiopharmaceutical dressing therapy is to make radionuclide dressing device to treat hemangioma, at present, it mainly includes 32P dressing device dressing therapy. 32P emits pure β-rays, and the maximum energy of its β-particles is 1.71MeV, and most of them are absorbed in the depth of 3-4mm of tissues. Advantages: According to the shape and size of the patient’s lesion, it can be made to adapt to the corresponding patient’s radioactive intensity, shape and size of the specificity of the dressing device. Disadvantages: the need for physicians to temporarily formulate, patients with long dressing time, the need for dressing dozens of hours. The treatment program is divided into: a large dose method: a complete course of treatment of the total dose, the need for physicians have a wealth of experience and accurate judgment. The advantage is that only one or two treatments are needed, which is easy for patients to accept. The disadvantage is the high chance of acute skin reactions. Split dose method: The total radiation dose is divided into several times, each time a smaller dose, suitable for facial areas and special parts of the lesions. Advantage is that the reaction is small and easy to observe. The disadvantage is that the treatment period is long and troublesome. Regardless of which method is used, it is currently believed that the radiation dose should be individualized. Compression therapy has the best effect on strawberry hemangioma (97.5% cured), with a small irradiation dose and a short treatment period, which may be related to the fact that strawberry hemangiomas are mainly composed of proliferating vascular endothelial cells, which have a good sensitivity to rays, as well as to the physical properties of beta rays. Bright red nevus is less sensitive to rays and has a lower cure rate. Bright red nevus is one of the more stubborn types of hemangioma, poorly treated with compresses and well treated with dye laser. Cavernous hemangioma occurs under the skin and mucous membranes, with a wider range or deeper site, and is a mauve or purple-blue subcutaneous nodule. This kind is mainly formed by veins, the ray is not easy to reach, the absorbed dose of β-ray is limited, the effect of isotope dressing treatment is not ideal, often need to be repeatedly irradiated many times; deep cavernous hemangiomas in the muscle layer, the dose of β-ray is very small, this kind of hemangioma can be used in vivo injection of isotope 32 phosphorus hemangioma treatment. Mixed hemangiomas mostly exist in the form of strawberry and cavernous hemangiomas, and cavernous hemangiomas are usually only in the subcutaneous and submucous membranes, so the effect of isotope dressing alone is unsatisfactory, and it is necessary to cooperate with isotope 32 phosphorus hemangioma in vivo injection treatment. We statistically found that the cure rate of simple capillary hemangiomas in children < 6 months old was as high as 97.5%, and most of them could be cured after the first course of treatment. This may be related to the fact that when the children are young, the hemangioma develops quickly and is sensitive to radiation; with the increase of age, the lesion develops slowly and is less sensitive to radiation, etc. Therefore, the treatment of pediatric hemangioma, especially strawberry hemangioma, should be detected as early as possible, and the earlier the treatment, the better. The treatment should pay attention to the following problems: ① Choose to do it when the child is sleeping or breastfeeding, so that the irradiated part can be fixed easily and the continuity of the treatment can be guaranteed. ② For children with large hemangioma area, the area should be marked and divided in advance so as to avoid omission of irradiation or more irradiation, and at the same time, attention should be paid to the junction of two areas so as to avoid overlapping irradiation or omission of irradiation in the area, which will affect the therapeutic efficacy. Special attention should be paid to the potential lesion area at the outer edge of the tumor, and its treatment range should be slightly larger than the edge of the tumor visible to the naked eye. (iii) Inform parents of the possible situations that may arise from the treatment and how to deal with the situation when it occurs. The affected area should not be washed with soap and hot water or scratched to avoid ulceration. Once the skin is broken, it is easy to form chronic radiation dermatitis or ulcers, which are more difficult to heal. If the skin has been broken, the dressing treatment should be stopped, and the treatment should be given to JinYinTi and BaiduBang ointment, and if necessary, the treatment should be changed in the surgical department. ④ For the treatment of facial hemangioma, special care should be taken to avoid the sequelae of skin injury caused by excessive irradiation. Practice has proved to be slightly conservative is appropriate, may need a small dose of multiple treatments, try to avoid the emergence of wet erythema or infection. In the clinical work, often encountered patients' parents are particularly anxious, and even asked the physician to increase the therapeutic dose, in order to cure as soon as possible. Special reminder: isotope application treatment is a chronic, painless treatment, the patient's parents need to have patience, need to listen to the physician's advice, not because of repeated follow-up and fear of trouble! Physicians should be more scientific and rigorous medical attitude, carefully formulate treatment plans, and carefully communicate with the patient's parents.