A comprehensive TCM program was developed around four key issues in the perioperative period of colorectal cancer, namely, improvement of surgical tolerance, recovery of bowel function, tissue healing, and improvement of quality of life. The comprehensive TCM program includes: preoperative benefitting Qi and strengthening the spleen to improve surgical tolerance, early postoperative benefitting Qi and widening the bowel to promote bowel function recovery, middle postoperative benefitting Qi and nourishing blood to promote anastomotic healing, and late postoperative benefitting Qi and strengthening the spleen to promote quality of life improvement. Pre-operative stage (3-5 days before surgery) (a) Objective: To improve surgical tolerance by applying the method of benefiting Qi and strengthening the spleen. (2) Methods: 1. Chinese herbal injection: Ginseng Astragalus injection 20ml plus 5% glucose injection 250ml intravenously once a day. Conrad injection 200ml slowly and quietly once a day. 2, Chinese medicine oral agent: apply Chinese medicine soup Si Jun Zi Tang plus reduction, take orally, one dose daily. 3.Acupuncture: take Qihai, Baihui, and Foot Sanli, once a day. Early postoperative stage (1~5 days after surgery) (a) Objective: to promote intestinal function recovery by applying the method of Yi Qi and wide bowel. (2) Methods: 1. Chinese medicine injection: Ginseng Astragalus injection 20ml plus 5% glucose injection 250ml intravenously once a day. Conrad injection 200ml slowly intravenous drip once a day. 2, Chinese medicine oral agent: apply Chinese medicine soup (Astragalus, Radix Angelicae Sinensis, Atractylodes Macrocephala, Pericarpium Citri Reticulatae, Citrus Aurantium, Lycopodium, He Shou Wu, etc.), orally, one dose per day, 100ml through the gastric tube, clamp the gastric tube closed and open it after 1 hour; twice a day. 3 .Acupuncture: take Foot San Li, Tian Shu, Upper Ju Xu, Lower Ju Xu, Neiguan, Zhong Guan, etc., once a day. 4.External application of traditional Chinese medicine: take cinnamon, clove, hedgehog, galangal, curcuma and sulforaphane, etc. and grind them together, make a paste with appropriate amount of yellow wine, and apply it to Shen Que point or large intestine point. (1) Objective: To promote tissue healing by applying the method of benefiting qi and nourishing blood. (2) Methods: 1. Chinese medicine injection: Ginseng Astragalus injection 20ml plus 5% glucose injection 250ml intravenously once a day. Conrad injection 200ml slowly intravenous drip once a day. 2, Chinese medicine oral agent: apply Chinese medicine soup ten whole tonic soup plus reduction (astragalus, cinnamon, ginseng, poria, atractylodes, rehmannia, angelica, white peony, chuanxiong, xiangxiang, sand, licorice, etc.), orally, one dose per day. 3 .Acupuncture: take Foot San Li, San Yin Jiao, Blood Sea, Neiguan, Zhong Guan, etc., once a day. (4) Late postoperative stage (11~15 days after surgery) (1) Objective: To improve the quality of life by applying the method of benefitting Qi and invigorating Blood. (2) Methods: 1. Chinese medicine injection: Ginseng Astragalus injection 20ml plus 5% glucose injection 250ml intravenously once a day. Add 5％ glucose injection 400ml intravenous drip once a day. 2, Chinese medicine oral agent: apply Chinese medicine soup Yi Qi and Blood circulation soup plus reduction (Astragalus, Angelica, Salvia, He Shou Wu, Fructus Lycii, Chen Pi, Sha Ren, Chicken Nei Jin, etc.) orally, one dose per day. 3, acupuncture: take foot San Li, Qi Hai, San Yin Jiao, Zhong Gui, etc., once a day.