Meniere’s disease, the standardized name is Meniere’s disease, is a kind of idiopathic membrane labyrinth accumulation caused by the inner ear disease, its cause is not yet clear, the main consideration is the mechanical obstruction of the endolymphatic ducts and endolymphatic absorption obstruction, immune reaction, inner ear ischemia, other causes, and so on. 1. Mechanical obstruction of endolymphatic ducts and endolymphatic absorption disorder: Any stenosis or obstruction in any part of the endolymphatic circulation, such as congenital stenosis and endolymphatic sac dysplasia, can lead to mechanical obstruction of endolymphatic ducts or endolymphatic absorption disorder, which can result in the appearance of the membranous labyrinthine hydrops. 2. Immune response: In recent years, a large number of studies have proved that the inner ear can receive antigenic stimulation and produce immune response, so that the antigen that enters into the inner ear in different ways or is produced by the inner ear itself stimulates the immune-active cells gathered around the blood vessels, endolymphatic ducts and endolymphatic sacs to produce antibodies, which causes the phenomenon of hydrops of the membranous labyrinth. 3. Ischemia of the inner ear: autonomic dysfunction and spasm of small blood vessels in the inner ear can lead to microcirculation disorders in the inner ear and the endolymphatic sac, resulting in tissue hypoxia, metabolic disorders, and the migration of fluid from the external lymphatic fluid and the blood, which can lead to the accumulation of fluid in the membranous labyrinth. 4. Other causes: In addition, dysfunction of the endolymphatic sac can also cause abnormal secretion or production of glycoproteins, leading to abnormal internal environment of endolymphatic stabilization; secondly, viral infections can also destroy the endolymphatic ducts and endolymphatic sacs, thus leading to hydrops of the membranous labyrinth. In addition, exertion, mental stress, emotional fluctuations, etc. can also trigger Meniere’s disease, so we should pay attention to preventive work in our daily life, and consult a doctor in time if we feel unwell.