An LDL of 4.46 mmol/L is a significant elevation, which is more serious and requires the initiation of lipid-lowering with drugs such as atorvastatin. LDL is mainly responsible for transferring cholesterol produced by the liver. If there is too much LDL, it will be combined by phagocytes and deposited in blood vessels, turning into arterial plaques and leading to atherosclerosis, which can lead to coronary heart disease, cerebral infarction, myocardial infarction and other serious diseases. The normal range of LDL is 2.0~3.12mmol/L, LDL 4.46mmol/L indicator is higher, especially the existence of diabetes, hypertension and other chronic diseases, people are more likely to atherosclerosis and other diseases, need to be under the guidance of the doctor to use drugs such as atorvastatin treatment, with a low-fat diet, appropriate exercise to improve.