Small fleshy bumps at the urethral orifice are considered as possible lesions such as urethral polyps, cysts, urinary tract infections, and acromegaly. It is recommended that patients can visit the urology department of the hospital for an examination to help clarify the diagnosis and deal with it in a timely manner. Common causes can be seen in the following areas: 1, urethral polyps: occur mostly related to infection, catheter location and trauma and other factors, mostly manifested as red tumor-like material located in the urethra, often also accompanied by for urinary frequency, painful urination, urinary difficulties, hematuria and other symptoms, some patients can also be without any symptoms. It can be treated by surgery, laser, electrocautery and other methods, most patients can be cured, the prognosis is good; 2, urethral cyst: related to trauma, infection, etc., mainly manifested as a cystic mass at the urethral orifice, if the cyst is small can be followed and observed, temporarily do not deal with, if the cyst is larger or appear pain, urinary frequency, painful urination, urinary difficulties and other symptoms should be timely surgery; 3, urinary tract infection: such as urethritis can also cause the phenomenon of small fleshy bumps in the urethra, usually also accompanied by frequent urination, urinary urgency, painful urination and other symptoms, mostly caused by bacteria, fungi, mycoplasma, chlamydia and other pathogens infection. The actual fact is that you can find a lot of people who are not able to get a good deal on a lot of things. The main treatment includes topical drugs, physical, surgical and other ways to remove warts; 5, pearl rash: the cause of this disease is unknown, may be due to local irritation caused by the penile coronal groove near, visible pearly white, yellow or light red papules. If the patient insists on removing it, the lesions can be removed by laser or freezing; 6, penile cancer: if the patient is male, it may be penile cancer, which may be related to factors such as circumcision, long foreskin and human papilloma virus infection. The main manifestation is that nodules or lumps can be palpated on the mucous membrane of penile head, coronal sulcus and inner plate of foreskin, and with the development of the disease, penile rupture, pain and abnormal discharge may appear. Early treatment is needed to surgically remove the lesion, and some patients may also need radiotherapy.