Gastroesophageal reflux disease needs to be treated with regular acid suppressing and motivating medications, but also with diet and lifestyle modification, all three of which are essential. If the disease does not heal over time, the cause must be found. The diet should not be too cold, too hard, too fast, too stimulating, too full, too greasy, too strong tea, coffee, chocolate, gas-producing drinks, etc. are not suitable. In some patients, eating seafood, garlic, overly fragrant food, etc. can aggravate the relaxation of the lower esophageal sphincter and increase the chance of reflux; it is recommended to have a clear and easy-to-digest mild diet, and temporarily refrain from eating fruits and cold drinks when the symptoms are heavy. Avoid drugs that stimulate the esophagus and stomach and relax the lower esophageal sphincter under the guidance of a doctor. In terms of lifestyle, avoid all factors that increase the pressure on the abdomen: sitting on low sofas, frequently bending over to carry heavy objects, excessive abdominal pressure when working out, standing upside down or with the head down and feet up, corseting, wearing a wide belt, eating within 3 hours before bedtime, etc. It is necessary to rule out eosinophilic esophagitis in patients with allergic rhinitis, pharyngitis, and asthma. Reflux can lead to extra-esophageal symptoms such as pharyngitis, rhinitis, cough, and vocal fold inflammation, especially at night, and treatment needs to be comprehensive. Avoid misdiagnosis.