Bromocriptine is currently the main drug for the treatment of pituitary lactation adenoma in China. But how should bromocriptine be taken? Since bromocriptine has certain side effects, mainly gastrointestinal reactions, dizziness, constipation, etc., about 10% of pituitary prolactinoma patients in the population have difficulty tolerating the side effects of bromocriptine. Therefore, when taking bromocriptine, you should start with a small dose. Depending on the size of the tumor and the blood lactation value, you can start with 1/4 tablet – half tablet daily, and take it with meals (first take a few bites of rice, then take the medicine, then continue to eat) or after meals, and if there is no reaction, gradually increase the dose after 3-5 days. After two years, you can try to reduce the dose and stop the medication, but after stopping the medication, most patients’ blood prolactin will increase again, so most patients may need to take the medication for life. Generally speaking, women with microprolactinomas usually need half to one tablet daily to bring their lactogen to normal, women with large lactinomas need about 1-3 tablets, and large lactinomas may require 3-6 tablets daily to control them. If 1 tablet per day is enough to control the blood lactogen at normal level, half a tablet in the morning and half a tablet in the evening can be taken orally, and the dose can be increased or decreased after half a month or a month according to the results of the lactogen review. 2 tablets each. If 6 tablets of bromocriptine per day still cannot bring the lactogen to normal, it is time to consider changing the medication to carte blanche. If it is not available in China, you need to buy it abroad or in Hong Kong. If you cannot get it, you have to choose surgery or surgery + radiotherapy. About 85% of patients with pituitary prolactin microadenoma or non-invasive pituitary prolactin adenoma can be cured endocrinologically after transsphenoidal surgery alone; invasive pituitary prolactin adenoma is basically difficult to be cured endocrinologically after transsphenoidal surgery alone and often requires postoperative drug therapy or radiotherapy.