Semen allergy needs to be treated with general measures, as well as medication and desensitization therapy. 1. General measures: women who experience perineal itching, burning pain, rash and other manifestations of semen allergy after intercourse need to stop intercourse in time, and then wash the perineum with water. 2. medication: for semen allergy patients can be under the guidance of the doctor with loratadine, cetirizine and other antihistamines. Some patients can also follow the doctor’s instructions to use hydrocortisone ointment, dexamethasone ointment and other glucocorticoid ointment. 3. desensitization therapy: if women are allergic to semen can be a small amount of contact with semen at first, and then gradually increase the amount of contact with semen, which is conducive to allowing the body to produce semen adaptation. It is recommended that patients with semen allergy first need to clean the perineum, for patients with severe allergy symptoms, need to consult a doctor in time, under the guidance of the doctor to choose the appropriate measures for treatment. In addition, patients usually need to use condoms during intercourse, which can avoid semen contact with the mucous membrane of the female vagina.