Tumor patients taking targeted drugs instead of pain, may be the side effect of drugs to kill tumor cells, or may not be related to the drugs, is caused by the patient’s own cancer pain, the pain is severe can take some analgesic drugs. General malignant tumor patients need to take targeted drugs, some patients taking targeted targeted drugs to kill cancer cells at the same time, may produce some adverse reactions, including pain, or the pain may have nothing to do with the drug, caused by the patient’s own cancer pain, if the pain is mild, it is recommended not to take analgesic drugs, so as to avoid premature development of resistance to analgesic drugs. If the pain is severe, some analgesic drugs can be taken, and the drugs should be used according to the principle of “three-step analgesic treatment for cancer pain”, such as aspirin and acetaminophen for mild pain, codeine and tramadol for moderate pain, and morphine and fentanyl for severe pain. The use of medication should be under the guidance of a doctor and should not be used without authorization.