Splenomegaly may be caused by splenic abscess, hemolytic anemia, and malignant lymphoma. It may cause shock, fever and other symptoms that are harmful to the human body. 1. Splenic abscess: Splenic abscess is usually caused by bacterial infection and other reasons. It may usually cause symptoms such as high fever, pressure and pain, splenomegaly, shock, and complications such as diffuse peritonitis, which are harmful to the human body. 2. Hemolytic anemia: Hemolytic anemia is usually caused by bacterial infection and other reasons. Symptoms such as fatigue, headache, hematuria, splenomegaly, and complications such as acute renal failure and impaired liver function may occur, which are harmful to the human body. 3. Malignant lymphoma: Malignant lymphoma is usually caused by infection, immune factors and other reasons. Symptoms such as fever, painless lymph node enlargement and splenomegaly may occur, which are harmful to human body. When the patient has splenomegaly, it is recommended to go to regular hospitals in time to clarify the cause of the disease and follow the doctor’s instructions for treatment.