Nutritional nerve treatment can be given to the fingers after chemotherapy, if it cannot be relieved or continues to worsen, the doctor should be consulted to adjust the chemotherapy program in time. The numbness and weakness of hands and feet and the inability to make a fist after chemotherapy may be caused by the neurotoxic effect of chemotherapeutic drugs, such as platinum chemotherapeutic drugs, 5-fluorouracil, which may be accompanied by numbness, dullness of sensation and abnormal sensation, paresthesia, painless or painful sensation, and skin swelling or erythema, etc. In general, the symptoms may improve with time. Generally speaking, the symptoms may improve with time, but also under the guidance of the doctor to take nutritional nerve drugs, such as vitamin B1, vitamin B12, methylcobalamin tablets. However, if the symptoms in the hands and feet continue to worsen and the medication is not effective, the doctor should be consulted to adjust the chemotherapy program.