Statins are not only effective in lowering cholesterol, but also in stabilizing and reversing plaque. Therefore, they are now commonly used in patients with atherosclerotic cardiovascular disease. For high blood lipids and to prevent the occurrence of cardiovascular disease, it is necessary to consider long-term statin use. Although statins are good, there are some potential risks if they are taken for a long time. Therefore, it is important to have a check-up after long-term use. The purpose of these tests is to find out how effective and safe the statin is. The first check-up should be within 1-2 months of taking a statin. The first check-up should not be too long apart. It is also important to know that the purpose of the first checkup is that the doctor needs to know whether the dosage is appropriate, whether the target lipid level has been reached, and whether some of the side effects of the statin are within acceptable limits. In the future, you can review your blood lipids and statin side effects once every 1-2 months, and then you can review them once every six months or so. Then the checkup items after taking statin for one year, mainly these are as follows: First, the risk of blood sugar increase caused by statins is about 10%, so it is necessary to check whether blood sugar is increased. Second, check the lipid level. Different lipid levels and concomitant diseases require different lipid target values; if the lipid does not meet the standard, it may be necessary to adjust the dosage or change the medication. Third, long-term statin use is likely to cause damage to kidney function, so kidney function check cannot be ignored, which directly affects the dosage of statin. Fourth, the incidence of sustained elevation of aminotransferase level during statin therapy is 0.5%-3.0%. Therefore liver function tests are also required. V. Liver enzymes and muscle enzymes, the more common and important side effects of statins are the effects of statins on liver enzymes and muscles. If you have muscle pain after taking statins, review them at any time. Sixth, pay attention to the presence of muscle pain, skin weakness, itching, rash, joint pain, insomnia, etc. The usual blood pressure situation is also needed.