The first thing you need to do is to take a blood test to check the HCG value to rule out pregnancy as a cause of delayed menstruation and chest swelling. If the HCG value rises, further gynecological ultrasound is needed to clarify whether it is an early intrauterine pregnancy or an ectopic pregnancy, and the next step of treatment will be decided according to the examination. If pregnancy is ruled out as the cause of delayed menstruation and chest swelling, further tests are needed to determine the sex hormone six test. If the test shows that FSH is rising, LH is rising and estrogen level is decreasing, sex hormone replacement therapy can be considered. If the sex hormone test is in the normal range, progesterone withdrawal therapy can be considered.