High percentage of basophils may be caused by allergic diseases, blood diseases, malignant tumors, and its treatment is different according to different causes. 1. Allergic diseases: such as food or drug allergy, urticaria, measles, etc., as well as bronchial asthma, rheumatoid arthritis and other diseases with hypersensitivity reactions. Treatment is mainly based on anti-allergic drugs, such as cetirizine and loratadine. 2. Blood diseases: chronic myeloid leukemia, basophilic leukemia and so on. The treatment method is based on different diseases, commonly used drugs such as Dasatinib and Nilotinib. 3. Malignant tumors: when metastatic cancer appears in malignant tumors, basophils will increase. It is mainly for the treatment of the original disease. In addition, diabetes, chicken pox, influenza, tuberculosis and other diseases may also have increased basophils. For the high percentage of basophils should go to the hospital to find out the cause, effective treatment for the cause, at the same time, the patient should follow the doctor’s instructions and actively cooperate with the doctor’s treatment, do not self-medication, in order to avoid delaying the condition or adverse reactions.