Thickening of nails may be due to physiological factors, but it may also be due to onychomycosis, nail dystrophy or nail changes caused by skin diseases. Different causes of different treatments, mainly antifungal, calcium and zinc supplementation, hormone therapy and other methods. 1. Physiological factors lead to the thickening of the nails is generally caused by aging, into the old age of the nails will become thick and cloudy, this situation generally do not need to be treated, you can trim the nails appropriately to make the nails thinner. 2. Nail thickening caused by onychomycosis can be oral antifungal drugs, such as terbinafine hydrochloride tablets, itraconazole capsules and so on. 3. Nail dystrophy is usually caused by trauma, exposure to chemicals or lack of trace elements such as calcium and zinc. It can be supplemented by oral medication such as multi-dimensional elemental tablets, calcium gluconate, zinc gluconate and so on. 4. Some skin diseases that grow on the fingertips, such as psoriasis and chronic eczema, can cause thickening of the nails, and active treatment of the primary disease can restore the nails. You can use glucocorticoid medication to apply and then seal the package treatment, such as tretinoin cream, mometasone furoate cream and so on. There may be other reasons for the thickening of nails, and it is recommended that the patient go to the hospital in time to get a clear diagnosis and symptomatic treatment.