To determine whether you have thalassemia, you need to start from family history, symptoms, hematological examination and genetic testing. 1. Family history: Thalassemia is a hereditary blood disease, so you can first find out if you have relatives with thalassemia in your family. 2. Symptoms: Patients with thalassemia may have pale face, weakness of limbs, yellowing of skin and sclera, or enlarged liver and spleen. In many cases, the symptoms of anemia appear from childhood. 3. Hematological examination: The blood routine of thalassemia will show microcytic hypochromic anemia, white blood cells and platelets are usually normal. Hemoglobin can also be analyzed by blood electrophoresis to help diagnose the disease. 4. Genetic testing: Genetic testing can identify abnormal gene fragments, which can help in the diagnosis of thalassemia. If there are symptoms of anemia, it is recommended to go to the hospital for examination in time, and the professional doctor will make a judgment by combining the clinical manifestations and relevant examinations.