Chicken skin, also known as “perifollicular keratosis”, is characterized by small, sharp follicular papules of normal skin color or reddish color, with follicular keratin plugs as its main feature. Currently, the treatment of this disease includes general daily care, drug therapy, physical therapy and so on. 1. General daily care: patients should reduce the use of irritating skin cleansers, pay attention to moisturizing, and can use moisturizing creams containing petroleum jelly, glycerin or lanolin ingredients. 1. Topical drug therapy: patients can use 0.1% retinoic acid cream, 10%~20% urea cool, 3%~5% salicylic acid ointment, etc. to soften or dissolve the keratin and improve the symptoms (this kind of drug has a certain degree of irritation, patients need to comply with the doctor’s instructions for use); lesions of the inflammatory response to the heavier can be combined with the use of topical medium-acting glucocorticosteroids. 2. Oral medication: vitamin A, vitamin E or small doses of vitamin A acid (it should be noted that people under 12 years of age, people with abnormal liver and kidney function, pregnant women, lactating women, and those who have a need for pregnancy in the past three months to two years are prohibited) can improve the symptoms. Pay attention to sun protection, which may irritate the skin and cause skin flaking. It is recommended that patients under the guidance of professional doctors, according to the specific conditions, receive appropriate treatment.