Numbness in the toes and feet may have the following causes: first, toe neuritis and toe neuroma, when there is toe neuritis and toe neuroma, it can also lead to numbness in the toes and feet, then the relevant examination and electromyography should be performed for diagnosis. Second, lumbar spine diseases, when the lumbar disc herniation, lumbar spinal stenosis compression of the nerve, can appear the palm of the foot, toe numbness, then to carry out the relevant lumbar spine X-ray, CT, nuclear magnetic examination, to carry out early diagnosis and treatment. Third, the peripheral nerve compression, peripheral nerve compression can also be in the peripheral nerve travel pressure, and lead to the palm of the foot, toe numbness, such as the tibial nerve compression, then the relevant examination and electromyography for diagnosis. Fourth, pear-shaped muscle syndrome, pear-shaped muscle syndrome can also be serious compression of the nerve and lead to numbness of the toes and feet, then we should conduct relevant physical examination and electromyography to diagnose and treat.