The treatment of erythema gangrenosum includes general treatment, such as elevation of the affected limb, etc.; medication, such as aspirin, propranolol, etc.; other treatments include physical therapy, closed treatment, etc. 1. General treatment. Patients should elevate the affected limbs, local cold compresses can relieve pain. 2.Drug treatment. (1) Antiplatelet aggregation drugs. If there is secondary thrombocytosis, small-dose aspirin can be taken orally. (2) Beta-blockers. Representative drugs include Pranolol, Atenolol and so on. (3) Prostaglandins. For example, misoprostol, etc., can relax the anterior capillary sphincter and improve blood circulation in the nutrient pathway to relieve symptoms. 3. Physical therapy. For example, ultrashort wave therapy, microwave therapy, etc. 4. Closure therapy. Can do sacral epidural closure, lumbar sympathetic ganglion block and so on. After suffering from erythema gangrenosum, you should go to the hospital for consultation and standardized treatment under the guidance of professional doctors.