High thyroid stimulating hormone index is considered to be related to hypothyroidism, pituitary microadenomas, drugs, etc. The treatments for different causes are different, and the patients can be treated with medication or surgery as prescribed by the doctor. 1. Hypothyroidism: low level of thyroid hormone in serum leads to increased reactivity of thyroid stimulating hormone, patients need to follow the doctor’s instruction to use levothyroxine sodium as a replacement therapy to maintain normal serum thyroid hormone level. 2. Pituitary tumor: Pituitary tumor secretes too much thyrotropic hormone, usually patients can follow the doctor’s instructions with bromocriptine, ergometrine and other drugs to control the hormone level, and some patients can cooperate with the doctor to remove the lesion through surgical means. 3. Drugs: Intake of lithium metal, potassium iodide, thyrotropin-releasing hormone can increase the thyrotropin hormone, can be taken under the guidance of the doctor to deal with the corresponding. It is recommended that people with high thyroid stimulating hormone undergo further detailed examination to clarify the cause and then follow the doctor’s instructions for treatment.