Low thyroid stimulating hormone and high other indicators may be the manifestation of hyperthyroidism; in addition, it can also be seen in the early stage of pregnancy, improper use of drugs and so on. 1. Hyperthyroidism: It is due to overactive thyroid function, which synthesizes and secretes too much thyroxine itself, thus inhibiting the release of thyrotropin. Thyroid function tests show decreased TSH and increased T3 and T4. Clinical manifestations of hypermetabolism in various systems, usually combined with enlargement of the thyroid gland. 2. Early pregnancy: Early pregnancy can secrete chorionic gonadotropin, which is similar in structure to thyroid-stimulating hormone and can stimulate the TSH receptor to raise thyroid hormone. Therefore, the increase of chorionic gonadotropin in early pregnancy can feedback inhibition of TSH, so there is a low TSH, T3, T4 increased performance. 3. Inappropriate use of drugs: common in post-thyroid surgery, thyroxine dosage is too large, causing exogenous supplementation of T3, T4 increase, inhibit the release of TSH. In short, the emergence of low thyroid stimulating hormone and other indicators of high, should be timely to the hospital, improve the relevant examination, under the guidance of the doctor for treatment.