Whether stage I or II membranous nephropathy can be cured is related to many factors, such as the type of pathology, whether the treatment is timely and appropriate, and comorbidities. Most patients can be remission or even cured, and a small number of patients have a poor prognosis. Primary membranous nephropathy, the etiology of which is unclear, is an immune-related renal disease, most of which can be remitted or even cured in stage I. Stage II is also better, and the therapeutic effect can be achieved, while the prognosis of some patients is poor. Untreated Stage I and II membranous nephropathy may be partially remissionable, but most of the disease will progress and even develop into uremia. The prognosis is especially poor for patients with persistent proteinuria, reduced renal function at the time of diagnosis, elderly, and female patients. Therapeutic drugs include hormones (e.g., prednisone acetate), immunosuppressants (e.g., cyclophosphamide, cyclosporine), renin-angiotensin-aldosterone receptor antagonists (valacyclovir, benadryl), and antithrombotic agents (warfarin, aspirin, etc.). All of the above drugs should be used in accordance with the doctor’s instructions, do not self-medication. Membranous nephropathy patients need to pay attention to regular follow-up in regular hospitals, regular testing of renal function, good renal function protection.