Generally speaking, pancreatic puncture takes about half an hour. Pancreatic puncture mainly includes preoperative preparation, intraoperative operation and postoperative care, the specific process is as follows: 1. Preoperative preparation: mainly, it is necessary to communicate with the patient to confirm whether the patient has recently used aspirin, clopidogrel and other coagulation drugs. And need to explain to the patient the surgical process and the risks involved, let the patient sign the informed consent. In addition, it is also necessary to check whether the patient’s blood routine and coagulation function meet the requirements of the operation, as well as the need to fast for more than 12 hours. 2. Intraoperative operation: During the operation, the patient should lie supine on the hospital bed, and the number, location and size of the lesions at the operation site should be observed by ultrasound or CT. After local anesthesia is completed, the puncture needle is inserted under the xiphoid process to obtain the desired tissue. 3. Post-operative care: After the surgery is completed, you need to observe the location of the surgery and the digestive tract to see if there is still bleeding, because the risk of bleeding will increase after the puncture. The procedure takes about half an hour, but you should consult your physician for details.