The department of care for uremia is usually nephrology. If there is conscious impairment, cardiac arrest, etc. then it is necessary to go to the emergency department immediately. Uremia is not a stand-alone disease, but rather a syndrome that is common to many types of advanced kidney disease and means that kidney failure has reached its terminal stage. Primary kidney disease, secondary kidney disease and hereditary kidney disease may cause serious damage to the renal units, making the kidneys unable to maintain their basic functions, resulting in impaired excretion of metabolic wastes and water from the body, which may lead to acid-base balance imbalance, water-electrolyte disorders, and systemic manifestations such as gastrointestinal tract, heart, lungs, nerves, skin, blood and other systemic manifestations. Patients with uremia should consult the nephrology department when they may have symptoms such as nausea, vomiting, edema, loss of appetite, or bloating, diarrhea, constipation, as well as lethargy, fatigue, or even dyspnea. If the patient has appeared consciousness disorder, delirium, or convulsions, cardiac arrest and other critical symptoms, need to go to the emergency department immediately. Uremia patients are recommended to go to regular hospitals in time, and given targeted treatment or therapy under the guidance of doctors.