Reader Mr. Rao wrote in to ask: I am 51 years old and often feel weak, sweaty, lose appetite, and sleep poorly, and have recently lost significant weight. His father died of lung cancer 1 year ago, and his current symptoms are similar to those his father had before the onset of the disease. He asked how he could determine whether he had a tumor, where he should go to see it and how to treat it. Deputy Chief Physician Guo Yuewu answered: In recent years, there is a trend of young tumor development, and there are often no specific symptoms in the early stage of tumor development, which is easy to be ignored by patients. Once specific symptoms appear, most of them are already in the middle and late stage, with poor efficacy and greatly reduced survival rate and quality of life. Therefore, regular medical checkups for specific groups of people are very necessary, which are of great significance for early detection, early treatment and saving lives of tumors. The specific groups of people who should receive regular medical checkup for tumor include: those with family history of tumor, those with long-term exposure to cancer-causing factors (physical factors such as radiation, chemical factors such as benzene), those with bad living habits (such as smoking), those with history of special microbial infections (such as H. pylori infection), and those with long-term malnutrition. Specialist physical examination for tumor is best done by oncologists, who will arrange the examination items reasonably according to the medical history, occupation and life condition provided by the examinee. Generally, it includes clinical physical examination, hematological examination (such as serum tumor markers), imaging examination according to medical history (such as X-ray, B-ultrasound, CT examination, etc.), interventional imaging examination (such as gastroscopy, etc.), tumor metabolic examination of nuclear medicine, etc. Medical checkups for specific people are performed at least once a year, and whether to increase the frequency of medical checkups is decided by oncologists based on the evaluation results of the current medical checkup. It is suggested that he should follow the tips in this article to complete the corresponding medical checkups as soon as possible, so that if problems are found, they can be dealt with early, and if there are no problems, the doubts can be solved early.