Sore throat when cold can use ibuprofen, pseudoephedrine hydrochloride and other drugs, at the same time should pay attention to lifestyle adjustments. When a cold occurs, if the pain in the throat is unbearable, you can use ibuprofen, acetaminophen and other antipyretic and analgesic drugs; if the sore throat is combined with dysphagia due to pharyngeal mucosal congestion and edema, you can orally use selective upper respiratory mucosal vasoconstrictor drugs such as pseudoephedrine hydrochloride. However, it should be noted that the above drugs can cause drowsiness and other adverse reactions, it is recommended to take before bedtime, aerial work, fine operation and other people are not recommended to use. At the same time, if the sore throat is combined with symptoms such as elevated blood count, pharyngeal pus and coughing up yellow sputum, suggesting bacterial infection, penicillin, cephalosporin and other antibacterial drugs can be used as appropriate treatment. In the use of medication at the same time, should pay attention to the strict cessation of smoking, avoid drinking alcohol, pay attention to rest, appropriate increase in drinking water, maintain air circulation, light diet. The above drugs need to be used under the guidance of clinicians, and unauthorized use of drugs is prohibited; the emergence of sore throat, fever and other cold manifestations, it is recommended to go to the fever clinic for treatment in a timely manner.