Is there a difference between laryngeal keratosis and laryngeal leukoplakia? No. It is called leukoplakia by clinicians because of its grayish-white appearance. However, its pathology is hyperkeratosis or incomplete keratinization, which is pathologically called keratosis, so laryngeal keratosis and laryngeal leukoplakia are the same disease. The otolaryngology published by the People’s Health Publishing House (a unified textbook of otolaryngology in national universities) introduces them as two separate diseases, but the etiology, symptoms and treatment of laryngeal keratosis and laryngeal leukoplakia are basically the same, so it is not appropriate to introduce them as two separate diseases. The laryngeal leukoplakia can occur in any part of the larynx, but the vocal cord leukoplakia is the most common, and other parts such as the leukoplakia in the interarytenoid area are rare, so the clinical use of vocal cord leukoplakia instead of laryngeal leukoplakia.