Forefoot pain may be caused by inappropriate shoes, plantar fasciitis, gout, fatigue fracture, callus hypertrophy, etc. It can be treated by general treatment, physical therapy, medication and surgery. 1. Unsuitable shoes: It is recommended that patients mainly rest, avoid standing or walking for a long time, use suitable shoes, try to avoid wearing high-heeled shoes or pointy shoes, to reduce the extrusion of the forefoot, so that the forefoot muscles can be relaxed, and alleviate the symptoms. Orthopedic shoes can also be used to elevate the arch of the foot, especially the transverse arch, which is conducive to pain relief. 2. Plantar fasciitis: It may be a sterile inflammation triggered by repeated minor injuries to the plantar fascia. If there are obvious pain symptoms, oral non-steroidal anti-inflammatory drugs, such as ibuprofen, diclofenac sodium, meloxicam, etc., can be taken to relieve the pain symptoms. Physical therapy such as shockwave and high-frequency electrotherapy can be used to relieve and eliminate inflammation. Functional orthopedic insoles can also be worn to elevate the arch of the foot to reduce the tension of the plantar fascia, which can promote the restoration of muscle strength and elasticity of the fascia. 3. Gout: Gout may be caused by hyperuricemia, which triggers the phenomenon of forefoot pain. During the acute development stage, non-steroidal anti-inflammatory drugs such as diclofenac sodium, indomethacin and etoricoxib can be taken orally to relieve the pain symptoms. Oral medications such as colchicine and glucocorticoids may also be taken. If necessary, surgical treatments such as elimination of gout stones and orthopedic treatment of deformed joints can be carried out. 4. Fatigue fracture: Fatigue fracture may be caused by long-term, repeated and minor injuries to the forefoot bones. Attention should be paid to rest, stop weight-bearing activities, avoid running, jumping and other activities that cause fracture pain. Protect the fracture site as much as possible, can plaster immobilize the affected area, elevate the affected limb to promote blood return. For patients with severe pain, non-steroidal anti-inflammatory drugs such as acetaminophen can be taken orally to improve the symptoms. 5. Callus hypertrophy: if the patient has serious callus hypertrophy, surgical treatment can be carried out to remove the hypertrophied callus to reduce the local compression, which can relieve the pain. It is recommended to consult a doctor in time, clear diagnosis, under the guidance of the doctor to use drugs, not blindly self-medication, in order to avoid adverse effects.