Numbness of the toes has more reasons, which may be related to peripheral neuritis, lumbar disc herniation, diabetes and so on. 1. Peripheral neuritis: may be due to infection, nutritional disorders, connective tissue disease and other reasons, causing inflammation of peripheral nerves, numbness of the toes can occur. 2. Lumbar intervertebral disc herniation: mostly due to lumbar intervertebral disc degeneration, nucleus pulposus protrusion, compression to the corresponding nerve root, causing unilateral or bilateral numbness of the toes. 3. Diabetes mellitus: mostly seen in patients with poor glycemic control, causing peripheral neuropathy, showing decreased sensation in the endings of the extremities, especially the endings of the lower extremities appear symmetrical numbness, coldness, pain. Toe numbness can also be seen in other causes, it is recommended that timely medical treatment, comply with the doctor’s instructions to carry out relevant examinations, with the help of the doctor to clarify the cause, and targeted treatment or treatment.