Some children with ischemic-hypoxic encephalopathy can grow up healthily, but in severe cases, sequelae such as mental retardation can occur. Ischemic-hypoxic encephalopathy is a disease in which newborns suffer from perinatal hypoxia and reduced cerebral blood flow due to a variety of reasons, resulting in brain damage. If the duration of ischemia and hypoxia is relatively short, there are no serious conditions such as convulsions or disorders of consciousness, and the duration of Apgar scores of less than three at birth is shorter than 15 minutes, then recovery is usually good and there may be no sequelae. However, if, on the contrary, the child has an Apgar score of less than three for a duration of more than 15 minutes, with concomitant convulsions, especially recurrent convulsions, with impaired consciousness lasting more than a week, and with persistent abnormalities on subsequent review of the electroencephalogram, the likelihood of sequelae is very high. Sequelae of neonatal hypoxic-ischemic encephalopathy include mental retardation, motor impairment as well as epilepsy and even cerebral palsy. If you have neonatal hypoxic-ischemic encephalopathy, it is important to treat it promptly.