Role of the pancreas

The pancreas is the second largest digestive gland in the human body and consists of an exocrine division and an endocrine division (pancreatic islets), which play an important role in the digestive process. The exocrine part of the pancreas constitutes the majority of the pancreas, which secretes pancreatic juice containing a variety of digestive enzymes. The pancreatic juice contains a variety of digestive enzymes secreted by the follicular cells, which are discharged into the duodenum through the ducts, and play an important role in the digestion of food. The alveolar cells also secrete a trypsin inhibitory factor that prevents trypsinogen from being activated in the pancreas. If this intrinsic mechanism is dysfunctional or if certain pathogenic factors cause trypsinogen to be activated in the pancreas, it will break down and destroy pancreatic tissues, leading to acute pancreatitis. The endocrine division is a cluster of cells scattered between the exocrine divisions, called islets, which secrete a variety of hormones into the blood or lymph, mainly involved in the regulation of glucose metabolism.